Catalog Search Results
Publisher
The Great Courses
Pub. Date
2021.
Language
English
Description
Learn how cells solve the problem of reading information in messenger RNA and using it to direct protein synthesis. Focus on how different parts of the translation apparatus work together through sequence-specific interactions. Also discover how antibiotics kill bacteria and what makes the bioterrorism agent ricin so deadly. Close by investigating techniques to create biological drugs on demand.
42) The Aging Brain
Publisher
The Great Courses
Pub. Date
2016.
Language
English
Description
We’re all getting older every day, and scientific research has shown that starting in our twenties, some brain functions begin a linear decline. But is old age all doom and gloom?..Not at all! While it’s true that some functions in the aging brain decline, neuroscientists have discovered that many other brain functions remain stable - or even improve - as we age. Furthermore, nurture plays as significant a role as nature, and there are a number...
Publisher
The Great Courses
Pub. Date
2021.
Language
English
Description
The products from the reactions in the previous lecture now enter the Krebs citric acid cycle. The outcome of these reactions, in turn, link to many other pathways, with the Krebs cycle serving as the hub directing the intricate traffic of metabolic intermediates. After decoding the Krebs cycle, use it to illuminate a deep mystery about cancer cells, which suggests new therapies for the disease.
44) Biochemistry and Molecular Biology: How Life Works: Episode 6,Hemoglobin Function Follows Structure
Publisher
The Great Courses
Pub. Date
2021.
Language
English
Description
Hemoglobin is the protein in red blood cells that carries oxygen from lungs to tissues and then takes away carbon dioxide for exhalation. Learn how structure is the key to this complicated and vital function. Also see how variant forms of hemoglobin, such as fetal hemoglobin and the mutation behind sickle cell anemia, can have life-saving or fatal consequences - all depending on structure.
Publisher
The Great Courses
Pub. Date
2016.
Language
English
Description
Aging affects us all, and it’s important to know how our cognitive functions change over our lives. The course opens with an examination of how fluid processing skills—such as episodic and working memory—tend to decline over time, whereas crystallized intelligence (how-to skills and accumulated knowledge) remains stable or even improves.
Publisher
The Great Courses
Pub. Date
2016.
Language
English
Description
How does memory work? Can aspects of it be improved? This eye-opening lecture offers a test of two different strategies for memorization: sheer repetition on the one hand, and visual-spatial storytelling on the other. Once you understand how memory works, you’ll investigate four key principles that you can apply to improve your own memory.
Publisher
The Great Courses
Pub. Date
2016.
Language
English
Description
Get ready for good news to help stave off mental decline! Here, you’ll analyze the effects of physical, social, and mental activity on the aging brain. Ample evidence from communities with longer-than-average lifespans shows that getting plenty of exercise and maintaining a vibrant social life can help keep the mind sharp and the spirit young.
Publisher
The Great Courses
Pub. Date
2021.
Language
English
Description
Trace the pathways of two widely ingested molecules: caffeine and fructose. Caffeine fools the body (usually harmlessly) into increasing glucose in the blood, while too much fructose can lead to unhealthy accumulation of fat in the liver. Then focus on two topics that link with the upcoming molecular biology segment of the series: androgen insensitivity and the molecular mechanisms of aging.
Publisher
The Great Courses
Pub. Date
2021.
Language
English
Description
Taught by Professor Kevin Ahern of Oregon State University, this series covers the essential topics of a first-semester college course in biochemistry and molecular biology, introducing you to amino acids, proteins, enzymes, genes, and the intricate workings of living cells. A background in high school-level chemistry is helpful.
Publisher
The Great Courses
Pub. Date
2021.
Language
English
Description
Close by surveying exciting developments in molecular biology that are now unfolding. One area has been dubbed "omics,"_x009d_ based on the explosion of applications due to genomics, which is the decoding of human and other genomes. Thus, we now have "proteomics,"_x009d_ "transcriptomics,"_x009d_ and other subfields, all exploiting our knowledge of the DNA sequences responsible for specific biochemical pathways.
Publisher
The Great Courses
Pub. Date
2016.
Language
English
Description
Find out what medical scientists mean by "dementia,"which results from disease and is not a normal part of healthy aging. The most prominent disease that causes dementia is Alzheimer’s, so Professor Polk walks you through its history, symptoms, and palliative treatments, as well as the current state of Alzheimer’s research.
Publisher
The Great Courses
Pub. Date
2021.
Language
English
Description
Get started on the subjects that Professor Ahern calls "the science of us"_x009d_: biochemistry and its allied field molecular biology, which both tell us who we are. Discover the handful of elements involved in biochemical reactions; the bonds they form; and the wide array of molecules that result, including amino acids, which are the building blocks of proteins.
Publisher
The Great Courses
Pub. Date
2021.
Language
English
Description
Adenosine triphosphate (ATP) is the fuel that powers many processes in living cells. Every day we make and break down our own body weight in ATP. Focus on the chemical reactions behind this impressive energy conversion system, which is governed by the Gibbs free energy equation. These reactions, which can proceed either forward or backward, are among the most important in biochemistry.
Publisher
The Great Courses
Pub. Date
2021.
Language
English
Description
Take a tour of cell manufacturing, focusing on metabolic pathways that use energy to synthesize key molecules, including sugars, complex carbohydrates, fatty acids, and other lipids. Along the way, learn why alcohol and exercise don't mix, how our bodies create short- and long-term energy stores, and why some essential fatty acids can lead to health problems if their ratios are not optimal.
Publisher
PBS
Pub. Date
2016.
Language
English
Description
Alzheimer’s disease strikes at the core of what makes us human: our capacity to think, to love, and to remember. The disease ravages the minds of over 40 million victims worldwide, and it is one of the greatest medical mysteries of our time. Join investigators as they gather clues and attempt to reconstruct the molecular chain of events that ultimately leads to dementia, and follow key researchers in the field who have helped to develop the leading...
Publisher
The Great Courses
Pub. Date
2016.
Language
English
Description
Continue your study of age-related brain diseases with an investigation of Parkinson’s disease and stroke. What are they? How do they affect a person’s behavior? And can they be treated? Examinations of these questions and more take you through neurochemistry, stem cell research, and strategies you can use to reduce your risk.
Publisher
The Great Courses
Pub. Date
2021.
Language
English
Description
When you touch a hot stove, you recoil instantly. How do nerve cells process information so quickly? Trace nerve impulses (which involve electrical signals and neurotransmitters) as they pass from neuron to neuron, and from neuron to muscle cells. Study molecules that block nerve transmissions, such as snake venom and Botox treatments, and look at the role of dopamine in addiction behaviors.
Publisher
The Great Courses
Pub. Date
2021.
Language
English
Description
Thus far, your investigations have accounted for only part of the energy available from food. So where's all the ATP? In this episode, see how ATP is produced in abundance in both animal and plant cells, largely via mitochondria (in animals and plants) and chloroplasts (in plants only). You also learn why we need oxygen to stay alive and how poisons such as cyanide do their deadly work.
Publisher
The Great Courses
Pub. Date
2021.
Language
English
Description
Molecular biology allows scientists and engineers to manipulate the recipes written in our genes. Spotlight some of the developments drawing on these techniques, including cloning, reprogramming cells, harnessing stem cells, and initiatives in "synthetic"_x009d_ biology, a new field that lets researchers create genomes that have never before existed, essentially fashioning entirely new life forms.
60) Biochemistry and Molecular Biology: How Life Works: Episode 7,Enzymes' Amazing Speed and Specificity
Publisher
The Great Courses
Pub. Date
2021.
Language
English
Description
Witness how structure and function are related in enzymes, which are a group of proteins that stimulate biochemical reactions to run at astonishing speed. One example is OMP decarboxylase, an enzyme that produces a crucial component of DNA in a blistering 0.02 second, versus the 78 million years that the reaction would normally take! Analyze the mechanisms behind these apparent superpowers.
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